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Related Concept Videos

Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

37
DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
37

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Related Experiment Video

Updated: May 6, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
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Active Rehabilitation Following Acute Mild Traumatic Brain Injury: A Systematic Review.

Briar Coman1, Dylan Powell2, Julia Das1,3

  • 1From the: Department of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle, United Kingdom.

Physiotherapy Canada. Physiotherapie Canada
|September 17, 2025
PubMed
Summary
This summary is machine-generated.

Early active rehabilitation after mild traumatic brain injury (mTBI) may speed recovery. This approach, involving exercise within one month of injury, appears safe and effective in reducing symptom duration compared to rest.

Keywords:
active rehabilitationconcussionexercisemTBI

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Area of Science:

  • Neurology
  • Sports Medicine
  • Rehabilitation Science

Background:

  • Mild traumatic brain injury (mTBI) management traditionally involves prolonged rest.
  • Extended rest may impede recovery and lead to persistent symptoms.
  • Emerging evidence supports early, symptom-guided active rehabilitation.

Purpose of the Study:

  • To review evidence on active rehabilitation interventions for mTBI recovery within one month of injury.
  • To evaluate exercise type, duration, and intensity in mTBI rehabilitation.
  • To recommend evidence-based rehabilitation protocols for acute mTBI.

Main Methods:

  • Systematic review of studies from PubMed, CINAHL, PsychARTICLES, SportDISCUS, and AMED.
  • Searched using terms like "mild Traumatic Brain Injury", "Rehabilitation", and "Acute".
  • Evidence appraised using Cochrane RoB-2 and ROBINS-I for risk of bias.

Main Results:

  • Seven papers reviewed from 434 initial citations; three were randomized controlled trials.
  • Active rehabilitation used varied protocols (treadmills, cycling) with different durations and intensities.
  • Active rehabilitation did not cause serious adverse events and generally did not worsen symptoms, decreasing recovery time compared to controls.

Conclusions:

  • Individualized active rehabilitation within one month post-mTBI is safe and effective for faster symptom resolution.
  • Further research is needed to establish consensus on specific intervention protocols for clinical practice.