A brain-health framework for PTSD: integrating digital biomarkers into multimodal assessment
Edel McGlanaghy1,2, Dylan Powell3, Tony Robertson4
1Adult Psychological Therapies, NHS Forth Valley Mayfield, Falkirk Community Hospital, Falkirk, UK.
NPJ Digital Medicine
|June 1, 2026
Abstract
None:
We propose a novel framework and measurement model that frames post-traumatic stress disorder (PTSD) in the context of brain health capital, utilising advances in smart devices (wearables, phones) and AI to better capture the multimodal physiological, behavioural, and cognitive features of PTSD. Patients would be provided with complex information in a meaningful way that could provide a unique opportunity to identify personal change mechanisms and support empowered, patient-led decision-making.
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Brain Imaging
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...


