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Updated: Jan 17, 2026

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
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High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels

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Characterization of Next-Generation Inhibitors for the Inward-Rectifier Potassium Channel Kir2.1: Discovery of

Renn A Duncan1,2, Daniel H Haymer1,2, Roman M Lazarenko3

  • 1Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee 37232, United States.

ACS Medicinal Chemistry Letters
|September 17, 2025
PubMed

Keywords:
SARdeuteriuminward-rectifier potassium channelmanual patch clamppharmacokineticsthallium flux

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