[New classification criteria for antiphospholipid syndrome: implications and clinical significance]

The new ACR/EULAR classification criteria for APS differ from the previous Sydney criteria by incorporating a broader range of clinical manifestations beyond venous/arterial thromboembolism and obstetric complications. These include microvascular disease, heart valve disease and thrombocytopenia. We applied both classification systems to a cohort of 139 individuals diagnosed with primary APS in Southern Sweden. Of these, 76 met the ACR/EULAR criteria, while 78 fulfilled the Sydney criteria. Subsequently, only a marginal difference in diagnostic yield was observed between the two classification systems. However, the ACR/EULAR criteria are particularly advantageous as they provide clear definitions and encompass a broader spectrum of clinical manifestations, aligning more closely with the clinical management of patients with APS compared to the Sydney criteria.