Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Improved use of laboratory diagnostic tests].

H Fiedler, S Zimmermann

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |December 1, 1985
    PubMed
    Summary

    Improving laboratory result interpretation relies more on pre-analysis standardization and diagnostic value than analysis quality. This enhances predictive value, crucial for accurate disease detection in patient populations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Grouping of PFAS for human health risk assessment: Findings from an independent panel of experts.

    Regulatory toxicology and pharmacology : RTP·2022
    Same author

    PSMA PET/CT with Glu-urea-Lys-(Ahx)-[⁶⁸Ga(HBED-CC)] versus 3D CT volumetric lymph node assessment in recurrent prostate cancer.

    European journal of nuclear medicine and molecular imaging·2015
    Same author

    Evidence for electroweak production of W±W±jj in pp collisions at sqrt[s] = 8 TeV with the ATLAS detector.

    Physical review letters·2014
    Same author

    Measurements of four-lepton production at the Z resonance in pp collisions at sqrt[s] = 7 and 8 TeV with ATLAS.

    Physical review letters·2014
    Same author

    [New anticancer drugs: much ado about nothing?].

    Revue medicale suisse·2014
    Same author

    Search for quantum black hole production in high-invariant-mass lepton+jet final states using pp collisions at √s=8  TeV and the ATLAS detector.

    Physical review letters·2014

    Area of Science:

    • Clinical chemistry
    • Laboratory medicine
    • Diagnostic interpretation

    Context:

    • Effective utilization of laboratory results is critical in healthcare.
    • Current practices may overemphasize analytical quality over pre-analytical and interpretative factors.
    • The diagnostic process relies heavily on accurate interpretation of laboratory data.

    Purpose:

    • To highlight the importance of pre-analytical standardization and diagnostic interpretation for effective laboratory result utilization.
    • To explain the role of disease prevalence in determining the predictive value of laboratory tests.
    • To emphasize the need for collaboration between physicians and laboratory scientists.

    Summary:

    • The effectiveness of laboratory results hinges on pre-analysis standardization and diagnostic interpretation, more so than analytical quality improvements.
    • The predictive value of a laboratory test, with constant sensitivity and specificity, is determined by the prevalence of the disease within the examined population.
    • Preceding general examinations like anamnesis and clinical examination increase disease prevalence, thereby enhancing the predictive value of laboratory results.

    Impact:

    • Improved diagnostic accuracy through better interpretation of laboratory findings.
    • Enhanced clinical decision-making based on more reliable predictive values.
    • Strengthened collaboration between clinical and laboratory professionals for better patient outcomes.

    Related Experiment Videos