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Updated: Jan 17, 2026

09:48
Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases
Published on: August 23, 2024
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Carbonic anhydrase-IX targeted copper-doped carbon dots as a theranostic probe for treating triple negative breast
Aftab Hossain Khan1, Sudeshna Pal1, Prasanta Kumar Das1
1School of Biological Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata-700032, India. bcpkd@iacs.res.in.
Abstract:
Herein, we demonstrate selective diagnosis and chemodynamic therapy in triple negative breast cancer (TNBC) cells by carbonic anhydrase-IX targeted acetazolamide-functionalized copper-doped carbon dots (CuCD-Az). CuCD-Az showed ∼3-fold higher cytotoxicity to TNBC compared to normal cells by ROS-mediated apoptosis via Fenton-like reaction.

