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Updated: Jan 17, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Normokalemic Littmann sign due to STEMI
János Tomcsányi1, Kristóf Tomcsányi1
1Department of Cardiology, Buda Hospital of the Hospitaller Order of St. John of God, Budapest, Hungary.
False double heart rate counting, a sign usually indicating hyperkalemia, can also occur in ST-elevation myocardial infarction (STEMI). This case highlights peaked T-waves in STEMI mimicking a critical electrolyte imbalance.
Area of Science:
- Cardiology
- Internal Medicine
- Medical Diagnostics
Background:
- The Littmann sign, characterized by double heart rate counting on electrocardiograms (ECGs), typically suggests severe hyperkalemia.
- Misinterpretation of ECG findings can lead to diagnostic delays and inappropriate management.
Purpose of the Study:
- To report a rare case of false double heart rate counting in ST-elevation myocardial infarction (STEMI).
- To highlight that peaked T-waves in STEMI can mimic the Littmann sign, potentially caused by computer error.
Main Methods:
- Case report presentation.
- Review of electrocardiogram (ECG) findings in a patient with anterior STEMI.
- Analysis of potential causes for artifactual ECG abnormalities.
Main Results:
- A patient with anterior STEMI exhibited ECG findings suggestive of double heart rate counting.
- This artifact was attributed to computer error and peaked T-waves, not hyperkalemia.
- The Littmann sign was mimicked, underscoring the importance of careful ECG interpretation.
Conclusions:
- The Littmann sign is not exclusive to hyperkalemia and can be observed in acute STEMI.
- Peaked T-waves in STEMI can lead to computer-generated false double heart rate counts.
- Clinicians must consider STEMI in the differential diagnosis of apparent Littmann sign to avoid diagnostic errors.
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