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Updated: Jan 17, 2026

Using the E1A Minigene Tool to Study mRNA Splicing Changes
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Using the E1A Minigene Tool to Study mRNA Splicing Changes

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Decipher RNA isoform combinations from minigene splicing assays and massive parallel sequencing with MAGIC

Camille Aucouturier1,2,3, Nicolas Goardon1,2, Laurent Castéra1,2

  • 1Laboratoire de biologie et de génétique du cancer, Département de Biopathologie, Centre François Baclesse, Caen 14000, France.

Bioinformatics (Oxford, England)
|September 19, 2025
PubMed
Summary

Minigene splicing assays are crucial for RNA variant analysis. MAGIC is a new tool simplifying the characterization of RNA isoforms from sequencing data, improving variant pathogenicity assessment.

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