Effects of Injectable Platelet-Rich Fibrin on the Osseointegration of Dental Implants

BACKGROUND Many methods are used to increase the osseointegration of dental implants. This study aimed to evaluate the effect of injectable platelet-rich fibrin (i-PRF) on the osseointegration of dental implants in 20 patients, as measured by resonance frequency analysis. MATERIAL AND METHODS The study included 20 patients, with each patient receiving 2 SLA implants. After preparing the 2 implant sockets in each patient, one socket was randomly selected and irrigated with i-PRF before implant placement, while the other socket was left untreated. Implant stability was evaluated using a frequency analysis device at a 3-month evaluation. RESULTS The initial implant stability quotient (ISQ) values of the implants in the the test group (i-PRF+) averaged 68.875±9.571, increasing to 74.237±8.283 after 3 months. In the control group (i-PRF-), the initial ISQ values averaged 73.275±7.699 and measured 73.662±8.089 after 3 months. The ISQ values of women in the i-PRF+ group were significantly higher than those of men (P=0.004), whereas no statistically significant difference was found between male and female patients in the i-PRF- group (P=0.399). No statistically significant difference was found in ISQ values based on bone density in either the test or control groups (test group, P=0.109; control group, P=0.430). CONCLUSIONS Implants treated with i-PRF demonstrated significantly higher stability values in resonance frequency evaluations compared to untreated implants. Additionally, while i-PRF application resulted in a significantly greater increase in stability in women than in men, bone density did not have an effect on stability.