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Related Concept Videos

Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis IV01:26

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Silicotuberculosis: Newer trends.

Ashish Ranjan1, Ajantha Panneerselvam1, Saroj Meena1

  • 1National Institute of TB and Respiratory Diseases, Sri Aurobindo Marg, New Delhi, 110030, India.

The Indian Journal of Tuberculosis
|September 20, 2025
PubMed
Summary
This summary is machine-generated.

Silicosis, an incurable lung disease from silica dust, increases risks for tuberculosis (TB). Early diagnostics and prevention are crucial for managing silicosis and silico-tuberculosis (Silico-TB).

Keywords:
Changing trendNPESSilicosisSilicotuberculosisTPT

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Area of Science:

  • Occupational Medicine
  • Pulmonology
  • Infectious Diseases

Background:

  • Silicosis, a progressive lung disease caused by silica dust inhalation, affects workers in mining, construction, and manufacturing.
  • New technologies increase silicosis cases, particularly in women, leading to significant social and economic burdens.
  • Silicosis impairs lung function and elevates risks for comorbidities like COPD, lung cancer, autoimmune disorders, and tuberculosis (TB).

Purpose of the Study:

  • To highlight the challenges in managing silico-tuberculosis (Silico-TB), the co-occurrence of TB in silicosis patients.
  • To emphasize the need for improved diagnostics and preventive strategies for silicosis and Silico-TB.
  • To underscore the importance of raising awareness regarding occupational hazards and exploring novel therapeutic options.

Main Methods:

  • Review of current diagnostic advancements for TB detection in silicosis patients, including rapid molecular and culture-based methods.
  • Adherence to National Tuberculosis Elimination Programme (NTEP) Guidelines for TB treatment and TB preventive treatment (TPT).
  • Discussion on the challenges in comprehensive management and prevention of Silico-TB.

Main Results:

  • Advances in diagnostics have improved TB detection rates in individuals with silicosis.
  • TB incidence is significantly higher in those with silica exposure, complicating diagnosis and treatment.
  • While TB treatment and prevention protocols exist, comprehensive Silico-TB management remains a challenge.

Conclusions:

  • Effective diagnostics and preventive measures are essential for combating silicosis and Silico-TB.
  • Raising awareness about occupational risks is crucial for reducing silica dust exposure.
  • Further research into innovative therapeutic options is necessary for better Silico-TB patient outcomes.