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Neurostructural Differences Associated With Prodromal Mania Symptoms in Children

Camille Archer1, Amy Milewski1, Hee Jung Jeong2

  • 1Department of Psychology, Vanderbilt University, Nashville, Tennessee, USA.

Brain and Behavior
|September 22, 2025
PubMed
Summary

Children with early mania symptoms show reduced gray matter volume, indicating smaller overall brain size. These brain structure differences may help identify youth at risk for bipolar disorder.

Keywords:
brain structurechildrengray matter volumemaniapathophysiology

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