Related Experiment Video
Updated: May 5, 2026

13:51
Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay
Published on: November 11, 2018
10.3K
Post-Myocardial Infarction Psychological Distress: A Scientific Statement From the American Heart Association.
Circulation
|September 22, 2025
Summary
Psychological distress is common after myocardial infarction and linked to worse cardiac outcomes. Interventions can improve well-being, emphasizing holistic patient care for cardiovascular disease patients.
Area of Science:
- Cardiology
- Psychology
Background:
- Psychological distress is a significant factor in cardiovascular disease (CVD) development and progression.
- Patients with acute myocardial infarction (MI) face elevated risks of depression, anxiety, and stress.
Purpose of the Study:
- To explore the impact of postmyocardial psychological distress on cardiac prognosis.
- To review mechanisms linking psychological distress to adverse cardiac events.
- To assess the evidence for treating post-MI psychological distress.
Main Methods:
- Literature review of studies on psychological distress in post-MI patients.
- Analysis of proposed biological and behavioral mechanisms.
- Evaluation of existing treatment outcome data.
Main Results:
- Up to 50% of post-MI patients experience psychological distress, increasing future cardiac event risk.
- Mechanisms include reduced physical activity, smoking, poor diet, and non-adherence to treatment.
- Data on improved cardiac prognosis with distress treatment are mixed and variable.
Conclusions:
- Post-MI psychological distress is prevalent and associated with poorer cardiac outcomes.
- Further research is needed, especially for anxiety, stress, and PTSD.
- Treating distress improves psychological health and quality of life, supporting holistic care.
Related Concept Videos
Acute Coronary Syndrome I: Introduction
2.1K
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
2.1K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
943
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
943
Acute Coronary Syndrome III: Diagnostic Studies
495
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
495
Acute Coronary Syndrome IV: Interprofessional Care
522
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
522
Angina I: Introduction
808
Definition and Symptoms: Angina (angina pectoris) is chest pain or discomfort caused by myocardial ischemia, which occurs when the heart muscle receives insufficient oxygen-rich blood. It typically manifests as pressing, squeezing, or crushing sensations in the chest and may radiate to the shoulders, arms, neck, jaw, or back.Primary Cause: In a healthy state, the coronary arteries can dilate (widen) to increase blood flow and meet the increased oxygen demand during physical activity or...
808
Angina III: Clinical Manifestations and Assessment
481
Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
481

