Keto-enol at play: regioisomerism regulated switching in indole-naphthyl Schiff bases
Savita Choudhary1, Adarash Kumar Shukla1, Sanjana Panyala1
1Department of Chemistry, Birla Institute of Technology and Science-Pilani (Hyderabad Campus), Hyderabad-500078, India. anupam@hyderabad.bits-pilani.ac.in.
Abstract:
Indole-naphthyl Schiff bases studied in this work show the importance of hydroxyl positions on enol (E)-keto (K) emissions, aggregation-induced emission (AIE), and viscosity-dependent emission properties. Single-crystal X-ray diffraction and computational studies provide insights into the structural properties of the tautomeric species. INpOH-1 and INpOH-2 demonstrated potential for distinguishing normal and cancer cells based on their polarity and viscosity sensitivity.
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