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Clinical spectrum of tuberculosis among HIV infected patients in India: Correlation with immunological status using
Snigdha M K1, Krishnavajhala Padma Theja1, Kondeti Ganga Bhavani1
1Department of General Medicine, ESIC Medical College, Sanathnagar, Hyderabad-500038, India.
Abstract:
Tuberculosis (TB) remains a common and serious opportunistic infection among HIV-infected individuals, with clinical presentation closely tied to immune status. In this prospective study of 100 HIV-positive patients with TB, pulmonary TB predominated in those with CD4 counts >200, while extra pulmonary and disseminated TB were strongly associated with CD4 counts <200. Symptoms such as cough and fever were prevalent and radiographic findings varied with immune suppression levels. CD4 counts served as a critical marker in determining the clinical spectrum and severity of TB. These findings underscore the importance of CD4-based assessment in guiding timely diagnosis and targeted management of TB in HIV patients.
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