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Association Between Body Roundness Index and Chronic Obstructive Pulmonary Disease in US Adults: Data from NHANES
Weibo Zheng1, Liandong Chen2, Haojie Ying3
1The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People's Republic of China.
International Journal of Chronic Obstructive Pulmonary Disease
|September 22, 2025
Summary
Higher body roundness index (BRI) is linked to an increased risk of chronic obstructive pulmonary disease (COPD) in US adults. This finding suggests BRI may help assess COPD likelihood.
Area of Science:
- Public Health
- Epidemiology
- Cardiorespiratory Medicine
Background:
- The relationship between body roundness index (BRI) and chronic obstructive pulmonary disease (COPD) prevalence in US adults is not well-established.
- Investigating this association is crucial for understanding potential risk factors for COPD.
Purpose of the Study:
- To examine the association between BRI and the likelihood of developing COPD in a US adult population.
- To explore the dose-response relationship and potential modifying factors in the BRI-COPD association.
Main Methods:
- Utilized data from the 2013-2018 National Health and Nutrition Examination Survey (NHANES).
- Defined COPD based on physician diagnosis, emphysema, or chronic bronchitis.
- Employed weighted logistic regression, restricted cubic spline (RCS) models, subgroup analyses, and interaction tests.
Main Results:
- A total of 14,254 participants were analyzed, with an 8.3% COPD prevalence.
- Continuous BRI showed a significant positive association with COPD (OR=1.140, P=0.012), confirmed by linear RCS analysis.
- Subgroup analyses revealed heterogeneity, suggesting sex, hypertension, and cardiovascular disease may influence the BRI-COPD link.
Conclusions:
- Elevated BRI levels are associated with a higher probability of COPD in US adults.
- BRI may serve as a valuable indicator for assessing COPD risk.
Keywords:
BRINHANESabdominal fatbody roundness indexchronic obstructive pulmonary diseasecross-sectional studyobesityMore Related Videos
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