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Successful Treatment of Childhood Nail Lichen Planus with Ruxolitinib Cream: A Case Report
Anqi Sheng1, Wenting Hu1, Ai'e Xu1
1Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, People's Republic of China.
Clinical, Cosmetic and Investigational Dermatology
|September 22, 2025
Abstract:
The role of oral JAK inhibitors in the treatment of nail lichen planus (NLP) has recently been reported, but there have been no literature reports on the treatment of NLP with topical Janus kinase (JAK) inhibitor. We present, for the first time, a preliminary clinical experience with topical ruxolitinib cream, a JAK inhibitor, in a child with NLP. The remarkable results suggest topical ruxolitinib cream may be a potential treatment option for NLP.

