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Updated: Jan 17, 2026

Digital Inline Holographic Microscopy DIHM of Weakly-scattering Subjects
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Trajectory imaging of low-contrast dynamic objects based on frequency-domain analysis.

Zhenguo Zhao, Xingbang Chen, Hongwei Wang

    Applied Optics
    |September 22, 2025
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    Summary
    This summary is machine-generated.

    Move contrast X-ray imaging (MCXI) effectively visualizes weakly absorbing object motion in complex settings. This robust technique enhances dynamic features without contrast agents, even in noisy environments.

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    Area of Science:

    • Physics
    • Imaging Science

    Background:

    • X-ray imaging struggles with low-contrast, overlapping objects in dynamic scenarios.
    • Capturing motion trajectories of weakly absorbing objects presents significant challenges.

    Purpose of the Study:

    • To introduce and evaluate move contrast X-ray imaging (MCXI) for enhanced dynamic feature visualization.
    • To demonstrate MCXI's robustness against noise and its ability to work without contrast agents.

    Main Methods:

    • Developed a fringe-based background model to simulate motion trajectory variations.
    • Employed quantitative metrics (trajectory intensity, integrity, SNR) for performance evaluation.
    • Integrated CUDA acceleration for efficient high-throughput data processing.

    Main Results:

    • MCXI successfully identified motion paths and spatial velocity distributions of weakly absorbing objects.
    • The method showed high robustness and sensitivity, even under high-noise conditions.
    • Experiments with oil-water motion validated the technique's effectiveness and noise resistance.

    Conclusions:

    • MCXI offers a robust solution for visualizing dynamic features of weakly absorbing objects in challenging environments.
    • The technique provides high sensitivity and noise resistance, outperforming traditional methods.
    • CUDA acceleration significantly enhances processing efficiency for dynamic X-ray data.