Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postoperative c-reactive protein resolution patterns in patients with and without postoperative atrial fibrillation after cardiac surgery.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

The Effect of Structured Context on Chest Radiograph Interpretation by a Multimodal Large Language Model: A Pilot Comparative Study.

Cureus·2026
Same author

Case report: failed restoration of left ventricular function after myosplint® placement followed by successful HeartMate 3™ LVAD implantation.

European heart journal. Case reports·2026
Same author

Impact of TAVR Failure Mechanism on Outcomes After Reintervention: From the EXPLANTORREDO-TAVR Registry.

Circulation. Cardiovascular interventions·2026
Same author

Biogenic polymer-based heart valve for congenital cardiac surgery.

JTCVS open·2026
Same author

Left ventricular assist device explantation after successful weaning in pediatric patients.

Multimedia manual of cardiothoracic surgery : MMCTS·2026
Same journal

Mitral valve anomalies in transposition of the great arteries.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

Oncologic Safety of Omitting Mediastinal Lymph Node Dissection in Segmentectomy for Ground-Glass Opacity-Dominant Lung Cancer: A Supplementary Analysis of JCOG1211.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

Progress in Thymic Malignancy Care: The Imperative for Global Standards and Collaboration.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

Association between interventional cardiologist practice characteristics, CABG use, and clinical outcomes.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

The EACTS Innovation Committee's Perspective on the "Heart Valve of the Future".

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

Why Should the Current Generation of Surgical Residents be Academically Active-Lessons From the Past.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
See all related articles

Related Experiment Video

Updated: Jan 17, 2026

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells
06:17

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells

Published on: March 28, 2025

1.0K

Biogenic Polymers for Congenital Cardiac Surgery: In Vitro Durability Testing.

Julian Hubrich1,2,3,4, Linda Grefen4,5, Alexandra Zorin2

  • 1Department of Congenital and Pediatric Cardiac Surgery, German Heart Center Munich, Technical University, Munich, 80636, Germany.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|September 23, 2025
PubMed
Summary
This summary is machine-generated.

Modified bacterial cellulose (BC) shows enhanced biomechanical resilience for congenital cardiac surgery (CCS) applications. This biomaterial demonstrates superior strength and durability, offering a promising alternative to current CCS materials.

Keywords:
bacterial cellulosebiogenic polymer-based materialscongenital heart disease

More Related Videos

Fabrication of Biologically Derived Injectable Materials for Myocardial Tissue Engineering
11:32

Fabrication of Biologically Derived Injectable Materials for Myocardial Tissue Engineering

Published on: December 20, 2010

15.5K
Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair
06:37

Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair

Published on: February 3, 2017

8.8K

Related Experiment Videos

Last Updated: Jan 17, 2026

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells
06:17

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells

Published on: March 28, 2025

1.0K
Fabrication of Biologically Derived Injectable Materials for Myocardial Tissue Engineering
11:32

Fabrication of Biologically Derived Injectable Materials for Myocardial Tissue Engineering

Published on: December 20, 2010

15.5K
Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair
06:37

Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair

Published on: February 3, 2017

8.8K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Cardiovascular Surgery

Background:

  • Current congenital cardiac surgery (CCS) materials lack growth, remodeling, and renewal capabilities, leading to suboptimal long-term outcomes.
  • Bacterial cellulose (BC), a biogenic polymer, exhibits excellent bio- and hemocompatibility, presenting a potential alternative for CCS applications.

Purpose of the Study:

  • To enhance the biomechanical resilience of bacterial cellulose (BC) for congenital cardiac surgery (CCS) applications.
  • To develop modified culturing conditions for BC to improve its suitability for CCS.

Main Methods:

  • Bacterial cellulose (BC) was produced and its biomechanical properties assessed via inflation pressure, thickness, and tensile testing.
  • Modifications included altering growth media composition and extending incubation time, followed by re-evaluation.
  • Long-term durability was tested using a fatigue tester for 20.5 million cycles, with structural integrity examined via scanning electron microscopy.

Main Results:

  • Modified BC patches withstood pressures over 1000 mm Hg with 100% durability, significantly outperforming standard BC at 500 mm Hg (20.8% durability).
  • Maximum tensile strength increased from 0.311 MPa to 0.986 MPa (P < .0001), and thickness increased to 3.89 mm (P < .0001).
  • Patches maintained structural integrity for 6 months in long-term durability testing without failure.

Conclusions:

  • Culturing modifications significantly enhance the biomechanical properties of bacterial cellulose (BC).
  • The improved BC demonstrates substantial potential for congenital cardiac surgery (CCS) applications.
  • Further investigation and development of this biomaterial are warranted for clinical translation.