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Updated: Jan 17, 2026

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High Precision FRET at Single-molecule Level for Biomolecule Structure Determination
Published on: May 13, 2017
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Advances in FRET methodologies for probing molecular interactions
Geetika Verma1, Vasanthi Jayaraman1
1Center for Membrane Biology, Department of Biochemistry and Molecular Biology, University of Texas Health Science Center at Houston, Houston, Texas.
Biophysical Journal
|September 23, 2025
Abstract:
Förster resonance energy transfer (FRET) has evolved into a powerful, quantitative approach for probing biomolecular structure, dynamics, and interactions. This research highlight brings together recent studies in Biophysical Journal that push the boundaries of traditional FRET. These innovations expand the spatial and temporal resolution of FRET, enabling its application to increasingly complex biological systems.

