Evaluation of Pediatric Cases With Cholelithiasis: 5-Year Single-Center Experience

Hilal Koyuncu1, Ayşe Tolunay Oflu1, Ayşe Güngör1

  • 1Department of Child Health and Diseases, Afyonkarahisar University of Health Sciences Faculty of Medicine, Afyonkarahisar, Turkey.

Clinical Pediatrics
|September 24, 2025
PubMed

Insights

Pediatric gallstones increase with age, often linked to obesity in adolescents. Abdominal pain is a common symptom, but incidental findings also occur. Clinicians should be cautious with medications in obese children.

Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Public Health

Background:

  • Gallstones (cholelithiasis) in children are increasingly recognized, presenting unique diagnostic and management challenges compared to adults.
  • Understanding the demographic and clinical profiles of pediatric gallstone patients is crucial for early detection and prevention strategies.
  • Obesity is a known risk factor for gallstones, and its rising prevalence in pediatric populations warrants specific investigation.

Purpose of the Study:

  • To investigate the demographic characteristics of pediatric patients diagnosed with gallstones.
  • To identify the common clinical presentations and underlying causes of gallstones in children.
  • To explore the relationship between age, obesity, and gallstone formation in the pediatric population.

Main Methods:

  • Retrospective analysis of pediatric patients diagnosed with gallstones between 2017 and 2023 at a tertiary hospital.
  • Data collection included patient demographics, clinical complaints, diagnostic findings, identified causes, and complications.
  • Statistical analysis was performed to determine the frequency, characteristics, and associations of pediatric gallstones.

Main Results:

  • A total of 65 pediatric patients were included, with a mean age of 10.8 years; 67.7% were adolescents.
  • Abdominal pain was the most frequent symptom (60%), while 33.8% were incidental findings.
  • Obesity was the leading identified cause (26.2%), significantly more prevalent in adolescents, and gallstone incidence increased with age.

Conclusions:

  • Gallstone prevalence in children rises with age, strongly associated with obesity, particularly in adolescents.
  • Symptomatic gallstones occurred in 69.2% of cases, with 15.3% experiencing complications.
  • Healthcare providers should consider obesity as a key factor in pediatric gallstones and exercise caution with potentially lithogenic medications in obese adolescents.

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