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Factors Influencing Heart Rate01:30

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The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
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Related Experiment Video

Updated: Jan 17, 2026

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
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Heart Rate Variability Responses in Children With Medical Complexity Across Sensory Domains.

Cindy Dodds1, Brooke Mulrenin1, Carrie Cormack2

  • 1College of Health Professions, Medical University of South Carolina, Charleston, South Carolina, USA.

International Journal of Pediatrics
|September 24, 2025
PubMed
Summary
This summary is machine-generated.

Heart rate variability (HRV) assessment offers insights into autonomic nervous system (ANS) health in children with medical complexity (CMC). This study reports reference respiratory sinus arrhythmia (RSA) values, finding gustatory stimulation and cerebral palsy impact ANS function in CMC.

Keywords:
autonomic dysfunctionautonomic nervous systemcerebral palsychildren with medical complexityheat rate variabilityparasympathetic regulationrespiratory sinus arrhythmia

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Area of Science:

  • Physiology
  • Autonomic Nervous System (ANS) Health
  • Pediatric Medical Complexity

Background:

  • Heart rate variability (HRV) is a key indicator of autonomic nervous system (ANS) health.
  • Children with medical complexity (CMC) often exhibit ANS dysfunction and reduced HRV.
  • Assessing CMC is challenging due to multisystem impairments.

Purpose of the Study:

  • To establish reference respiratory sinus arrhythmia (RSA) values derived from HRV in CMC.
  • To explore HRV as a potential method for assessing CMC and treatment efficacy.
  • To investigate ANS responses to sensory stimuli in CMC.

Main Methods:

  • 36 CMC (ages 5-21) were monitored using Firstbeat Bodyguard 2 devices.
  • Cardiac data collected during the Pediatric Assessment of Sensory Motor Awareness.
  • RSA values calculated using CardioEdit and CardioBatch software; statistical analysis performed.

Main Results:

  • Preliminary reference RSA values reported for CMC, including a subset with cerebral palsy (CP).
  • Gustatory sensory domain significantly reduced RSA compared to baseline and other domains.
  • Children with CP showed less autonomic dysfunction than non-CP CMC at baseline.

Conclusions:

  • HRV measurements provide valuable reference RSA values for CMC.
  • Gustatory stimulation negatively impacts RSA in CMC.
  • CMC demonstrate a learning effect with repeated assessments; HRV can monitor health and behavioral responses.