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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Endoscopic Mastectomy in Patients with Genetic Mutations
Guillermo G Peralta-Castillo1,2, Luis Miguel Cornejo-Mota1,3, Luis César Valencia-García1,3
1Breast Division, Hospital H+, Querétaro, Mexico. (Drs. Peralta, Cornejo, Valencia, and Bajonero).
JSLS : Journal of the Society of Laparoendoscopic Surgeons
|September 24, 2025
Summary
Endoscopic nipple- and skin-sparing mastectomy (eNSM) is a safe and effective procedure for high-risk patients with genetic mutations. This approach offers oncologic safety and high patient satisfaction with no reported complications or recurrences in our study.
Area of Science:
- Oncology
- Plastic Surgery
- Genetics
Background:
- Patients with germline mutations (BRCA1, BRCA2, CHEK2, MUTYH) face increased breast cancer risk.
- Nipple- and skin-sparing mastectomy (NSM) aims to improve cosmetic outcomes while maintaining oncologic safety.
- Endoscopic techniques may offer advantages in minimally invasive oncologic surgery.
