Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Operant Conditioning Intervention01:24

Operant Conditioning Intervention

459
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
459

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimising Multimodality Treatment of Resectable Oesophago-Gastric Adenocarcinoma.

Cancers·2022
Same author

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study.

Nature cancer·2022
Same author

Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study.

Nature cancer·2022
Same author

Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer.

Lancet (London, England)·2022
Same author

Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA.

Human genetics·2022
Same author

Effect of peri-operative chemotherapy regimen on survival in the treatment of locally advanced oesophago-gastric adenocarcinoma - A comparison of the FLOT and 'MAGIC' regimens.

European journal of cancer (Oxford, England : 1990)·2022

Related Experiment Video

Updated: Jan 17, 2026

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke
08:01

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

12.0K

Advancing Stroke Recovery Through Operant Conditioning of Corticomuscular Coherence.

Jasper I Mark1,2, David Cunningham3, Jessica M Cassidy1

  • 1Department of Health Sciences, University of North Carolina at Chapel Hill, Chapel Hill, USA.

Restorative Neurology and Neuroscience
|September 24, 2025
PubMed
Summary

This study proposes a novel stroke rehabilitation strategy combining operant conditioning with corticomuscular coherence (CMC) to enhance neuroplasticity and motor recovery. This approach aims to strengthen neural circuits and improve functional integration for better patient outcomes.

Keywords:
biofeedbackelectroencephalographyelectromyographyneurorehabilitationoperant conditioningstroke

More Related Videos

Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System
07:35

Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System

Published on: December 29, 2023

1.9K
Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies
05:28

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Published on: October 11, 2024

1.1K

Related Experiment Videos

Last Updated: Jan 17, 2026

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke
08:01

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

12.0K
Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System
07:35

Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System

Published on: December 29, 2023

1.9K
Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies
05:28

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Published on: October 11, 2024

1.1K

Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Neuroengineering

Background:

  • Stroke-induced deficits impact multiple functional domains, necessitating interventions promoting neuroplasticity.
  • Current rehabilitation strategies can be enhanced by targeting brain-body communication.
  • Corticomuscular coherence (CMC) serves as a neurophysiological marker for brain-muscle communication and volitional control.

Purpose of the Study:

  • To propose a novel rehabilitation strategy integrating operant conditioning with corticomuscular coherence (CMC) for stroke recovery.
  • To explore the potential of reinforcing CMC to enhance motor control and cognitive functions post-stroke.
  • To outline the conceptual framework, translational potential, and implementation challenges of this approach.

Main Methods:

  • A perspective piece outlining a rehabilitation strategy based on existing motor learning, systems neuroscience, and neuroengineering principles.
  • Focus on operant conditioning principles to reinforce corticomuscular coherence (CMC).
  • Utilizing CMC as a real-time index of volitional control to guide rehabilitation.

Main Results:

  • The proposed strategy offers a biologically plausible mechanism for enhancing neuroplasticity-like effects.
  • Reinforcing CMC through operant conditioning is hypothesized to strengthen movement-related neural circuits.
  • This approach may simultaneously engage cognitive systems involved in motor planning, attention, and error correction.

Conclusions:

  • The CMC-based operant conditioning framework presents a promising avenue for optimizing stroke recovery.
  • This strategy has the potential to strengthen residual motor capacity and restore functional integration.
  • Further research and clinical trials are needed to validate the translational potential and address implementation challenges.