Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intradural Fibrosis Following Percutaneous Spinal Cord Stimulator Placement: A Case Report.

Pain practice : the official journal of World Institute of Pain·2026
Same author

From compliance to prediction: Clinical laboratories as digital infrastructure for health-system quality and safety.

International journal for quality in health care : journal of the International Society for Quality in Health Care·2026
Same author

Coronal Spinal Deformity Does Not Predict Clinical Response to Thoracic Spinal Cord Stimulation.

Neuromodulation : journal of the International Neuromodulation Society·2026
Same author

Treatment Durability After Subdural Evacuating Port System, Middle Meningeal Artery Embolization, and Combined Therapy for Chronic Subdural Hematoma.

Neurosurgery·2026
Same author

The Practice of Cytopathology in India: Insights From a 2025 Nationwide Survey.

Diagnostic cytopathology·2026
Same author

Targeting CCR1 remodels the tumor microenvironment and relieves immune suppression in pancreatic cancer.

Cancer immunology research·2026

Related Experiment Video

Updated: Jan 17, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.8K

Asleep Deep Brain Stimulation for Essential Tremor.

Tessa A Harland1, Shruti Gupta2, Matthew Hefner3

  • 1Department of Neurosurgery, Albany Medical Center, Albany, New York, USA, harlant@amc.edu.

Stereotactic and Functional Neurosurgery
|September 24, 2025
PubMed
Summary
This summary is machine-generated.

Interventional MRI-guided deep brain stimulation (DBS) for essential tremor (ET) under general anesthesia is effective. This technique offers a viable alternative for patients anxious about awake surgery, improving tremor and quality of life.

Keywords:
Asleep deep brain stimulationEssential tremorMRI-guided deep brain stimulation

More Related Videos

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

11.4K
Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

9.3K

Related Experiment Videos

Last Updated: Jan 17, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.8K
Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

11.4K
Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

9.3K

Area of Science:

  • Neurosurgery
  • Neurology
  • Medical Technology

Background:

  • Deep brain stimulation (DBS) for essential tremor (ET) was FDA-approved in 1997.
  • Technological advancements have evolved functional neurosurgery techniques.
  • Interventional MRI-guided DBS lead placement is an emerging technique with limited data, particularly for targeting the ventral intermediate nucleus (VIM).

Purpose of the Study:

  • To review the experience of a single surgeon using interventional MRI-guided DBS targeting of the VIM in ET patients under general anesthesia.
  • To assess the feasibility and effectiveness of this technique in a community setting.

Main Methods:

  • Retrospective chart review of 113 ET patients undergoing MRI-guided DBS under general anesthesia (2016-2021).
  • Collected data included demographics, radial error, procedure details, complications, and clinical outcomes.
  • Outcome measures: medication reduction, Quality of Life in Essential Tremor Questionnaire (QUEST), and Fahn-Tolosa-Marín (FTM) tremor rating scale.

Main Results:

  • 175 DBS leads were placed with a mean radial error of 0.43 ± 0.33 mm.
  • 69.2% of patients stopped or reduced medication post-DBS.
  • Significant improvements observed in FTM scores (34.0 to 8.9) and QUEST Summary Index (47.1 to 29.4).

Conclusions:

  • Interventional MRI-guided DBS lead placement under general anesthesia is a feasible and effective treatment for ET.
  • This technique may broaden DBS accessibility for patients with anxiety about awake procedures.