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Related Experiment Video

Updated: Jan 17, 2026

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material
07:42

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material

Published on: December 20, 2024

764

Biophysical Properties of Three Light-cured Pulp Capping Materials.

Maa Fraga, Acp Janini, M M Nobre

    Operative Dentistry
    |September 24, 2025
    PubMed
    Summary

    Photoactivated pulp capping materials like Theracal, Hidrox-cal, and Ultra-Blend showed varied cell viability and limited bioactivity. While mechanical properties were good, cytotoxicity concerns remain for these dental materials.

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    Accessing the Cytotoxicity and Cell Response to Biomaterials
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    Area of Science:

    • Biomaterials Science
    • Dental Materials Research
    • Regenerative Dentistry

    Background:

    • Photoactivated materials are used for dentin-pulp complex treatments.
    • Assessing their biocompatibility and bioactivity is crucial for clinical success.
    • Theracal, Hidrox-cal, and Ultra-Blend are examples of such materials.

    Purpose of the Study:

    • To evaluate the cell viability, degree of conversion, compressive strength, and bioactive potential of three photoactivated dentin-pulp complex materials.
    • To compare the performance of Theracal, Hidrox-cal, and Ultra-Blend.
    • To determine the suitability of these materials for pulp capping applications.

    Main Methods:

    • Cell viability assessed using MTT assay.
    • Degree of conversion analyzed by Raman spectroscopy.
    • Compressive strength tested on a universal testing machine.
    • Bioactive potential evaluated via SEM and Raman spectroscopy after simulated body fluid immersion.

    Main Results:

    • Theracal showed the lowest cell viability compared to Hidrox-cal and Ultra-Blend.
    • Hidrox-cal exhibited a higher degree of conversion, similar to Ultra-Blend.
    • No significant differences in compressive strength were found among the materials.
    • Limited crystalline structure formation was observed for Theracal and Ultra-Blend, indicating restricted bioactivity.

    Conclusions:

    • Light-cured pulp capping materials possess adequate mechanical properties but demonstrate limited bioactivity and variable cytotoxicity.
    • Further research is needed to improve the biocompatibility and bioactivity of these dental materials.
    • Clinical performance may be affected by the observed cytotoxicity and limited regenerative potential.