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Maternal Quality of Life Following a Periviable Delivery
Juliann Wang1, Christina Blanchard2,3, Angela Seasely2,3
1University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL.
Ochsner Journal
|September 25, 2025
Summary
Maternal quality of life after periviable infant delivery varied. Mothers with surviving infants reported better psychological and social well-being compared to those with infant demise, though overall quality of life was similar.
Area of Science:
- Perinatal medicine
- Maternal health outcomes
- Quality of life research
Background:
- Limited data exists on long-term maternal quality of life after periviable infant delivery.
- Periviable delivery, typically between 22 and 25 weeks gestation, presents unique challenges for mothers.
- Investigating maternal well-being is crucial for comprehensive perinatal care.
Purpose of the Study:
- To assess and compare long-term quality of life in mothers who delivered periviable infants.
- To identify differences in quality of life domains based on infant survival status.
- To provide insights into the psychosocial impact of periviable birth on mothers.
Main Methods:
- Retrospective cohort study of 58 mothers delivering periviable infants (22-25 weeks gestation).
- Utilized the World Health Organization Quality of Life-Brief Version (WHOQOL-BREF) questionnaire.
- Compared quality of life scores between mothers with surviving infants and those with intrauterine or neonatal demise.
Main Results:
- Mothers with surviving infants had significantly lower maternal age.
- Mothers of surviving infants reported higher quality of life in psychological health and social relationships domains.
- While mothers of survivors were more satisfied with their health, overall quality of life did not differ significantly between groups.
Conclusions:
- Mothers whose infants survived periviable delivery reported improved psychological and social well-being.
- Despite potential infant health complications, survival can positively influence certain aspects of maternal quality of life.
- Further research with larger cohorts is warranted to confirm these findings.

