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Related Concept Videos

Hypersensitivities01:30

Hypersensitivities

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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Allergic Reactions02:06

Allergic Reactions

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Overview
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Allergic Drug Reactions01:27

Allergic Drug Reactions

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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Stress perception of occupational dermatology patients: a qualitative interview study.

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[How classification and guidelines simplify the care of pruritus patients. A guest commentary].

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Related Experiment Video

Updated: Jan 6, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
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A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

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[Allergy or atopy-occupational dermatitis is often more complex than initially thought].

Nathalie-Christin Kaul1, Elke Weisshaar2

  • 1Sektion Berufsdermatologie, Zentrum Hautklinik, Universitätsklinikum Heidelberg, Voßstr. 2, 69115, Heidelberg, Deutschland. nathalie-christin.kaul@med.uni-heidelberg.de.

Dermatologie (Heidelberg, Germany)
|September 25, 2025
PubMed
Summary

A patient developed hand eczema after changing jobs. Despite a diagnosed epoxy resin allergy, the eczema persisted even in an epoxy-free environment, suggesting atopy can manifest as hand eczema later in life.

Area of Science:

  • Dermatology
  • Occupational Medicine
  • Allergology
Keywords:
Contact dermatitisEczemaItchingType IV sensitivityVesicular hand eczema

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