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Comparison of 1-Year Clinical and Radiographic Outcomes Between 2 Expandable Cage Designs in Navigation-Assisted
Khanathip Jitpakdee1,2, Chibuikem A Ikwuegbuenyi1, Minaam Farooq1
1Department of Neurological Surgery, Och Spine at NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA.
International Journal of Spine Surgery
|September 25, 2025
Summary
Expandable cages that improve both disc height and lordosis in minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) provide superior segmental lordosis restoration. Both cage types yield similar clinical outcomes and high fusion rates.
Area of Science:
- Spine surgery
- Orthopedic surgery
- Biomedical engineering
Background:
- Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) often faces challenges in restoring adequate lordotic alignment.
- Expandable cage design, specifically height and lordotic angle, is crucial for successful outcomes.
- This study compares two MIS-TLIF expandable cage designs: one enhancing disc height only (Group H) and another enhancing both height and lordosis (Group HL).
Purpose of the Study:
- To compare the efficacy of two expandable cage designs in MIS-TLIF for restoring spinal alignment and clinical outcomes.
- To evaluate the impact of cage design on segmental lordosis, disc height, subsidence, and fusion rates.
- To assess the clinical relevance of surgeon experience in mitigating cage subsidence.
Main Methods:
- A retrospective review of 75 patients undergoing navigation-assisted MIS-TLIF with expandable cages.
- Patients were divided into two groups: Group H (35 cases, height-only expansion) and Group HL (40 cases, height and lordosis expansion).
- Clinical outcomes (pain scores, Oswestry Disability Index) and radiographic parameters (disc height, lordosis, subsidence, fusion) were analyzed.
Main Results:
- Both groups demonstrated significant clinical improvement, with no intergroup differences.
- Group HL showed significantly greater improvements in segmental lordosis and disc angle at 1-year follow-up compared to Group H.
- Overall fusion rate was 92%, with an initial subsidence rate of 32% decreasing to 20% with experience.
Conclusions:
- Expandable cages designed for both height and lordosis expansion in MIS-TLIF offer superior segmental lordosis improvement.
- Both cage designs achieve high fusion rates and comparable clinical outcomes.
- Surgeon experience is vital for minimizing cage subsidence and optimizing clinical results.

