Related Experiment Video
Updated: Jan 16, 2026
Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
Retrograde and Contralateral Metastasis of Clear Cell Renal Cell Carcinoma to the Spermatic Cord: A Case Report
Joy M Hoang1, Munira Charania2, Marcus L Quek3
1Department of Pathology, Loyola University Medical Center, Maywood, USA.
Abstract:
Clear cell renal cell carcinoma (ccRCC) is known to display synchronous and metachronous metastases to a diverse set of organs. Retrograde and contralateral metastases of ccRCC are rare, with few cases in the literature. The mechanism of spread in these cases is thought to be facilitated by either the direct extension of tumor into the renal and gonadal veins or by the vertebral venous plexus. Here, we present a rare case of contralateral and retrograde ccRCC metastasis with extensive venous involvement.
Insights
Retrograde and contralateral metastases of clear cell renal cell carcinoma (ccRCC) are rare occurrences. This study presents an unusual case of ccRCC metastasis involving extensive venous spread to contralateral and retrograde sites.
Area of Science:
- Oncology
- Urology
- Pathology
Background:
- Clear cell renal cell carcinoma (ccRCC) commonly metastasizes to various organs.
- Retrograde and contralateral ccRCC metastases are exceptionally rare, with limited documented cases.
- Potential mechanisms include tumor extension into renal/gonadal veins or via the vertebral venous plexus.
More Related Videos
06:38A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
06:28Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
Published on: May 27, 2022
