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Psychiatric Manifestations in a Postmenopausal Woman Caused by Prolonged Testosterone Pellet Therapy
Naveena Daram1, Morgan Wilhoite1, Emily Hurley1
1Department of Obstetrics and Gynecology, Wright State University, Dayton, and the Department of Reproductive Endocrinology and Infertility and the Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio.
Long-term testosterone therapy in postmenopausal women may lead to severe psychiatric symptoms like anxiety and delusions. Careful monitoring of hormone replacement therapy is crucial for patient safety.
Area of Science:
- Endocrinology
- Psychiatry
- Women's Health
Background:
- Supplemental testosterone therapy is common for postmenopausal women experiencing low libido, fatigue, bone density loss, and muscle weakness.
- The long-term effects of testosterone supplementation in this demographic remain incompletely understood.
- Hormone replacement therapy requires careful consideration due to potential systemic effects.
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