Psychiatric Manifestations in a Postmenopausal Woman Caused by Prolonged Testosterone Pellet Therapy

Naveena Daram1, Morgan Wilhoite1, Emily Hurley1

  • 1Department of Obstetrics and Gynecology, Wright State University, Dayton, and the Department of Reproductive Endocrinology and Infertility and the Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio.

O&G Open
|September 26, 2025
PubMed
Summary

Long-term testosterone therapy in postmenopausal women may lead to severe psychiatric symptoms like anxiety and delusions. Careful monitoring of hormone replacement therapy is crucial for patient safety.

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