Related Experiment Video

Updated: May 3, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

10.6K

Identification of the Novel HLA-B*08:339 Allele Using Next-Generation Sequencing Method

Elena Balducci1, Barbara Minotto1, Filomena Aquino1

  • 1Laboratorio HLA e Biologia Molecolare - Transfusion Medicine Department of Venezia - Ospedale dell'Angelo, AULSS SERENISSIMA, Mestre, Venezia, Italy.

HLA
|September 26, 2025
PubMed
Summary

A novel HLA-B*08:339 allele was identified, differing from HLA-B*08:25 by three mismatches in exon 3. These genetic variations result in three non-synonymous mutations, impacting protein structure.

Keywords:
HLA‐B*08:3393 mismatches in exon 3NGS

More Related Videos

Detection of Rare Mutations in CtDNA Using Next Generation Sequencing11:11

Detection of Rare Mutations in CtDNA Using Next Generation Sequencing

Published on: August 24, 2017

17.3K
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

31.1K

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
836