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Updated: Jan 16, 2026
Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
Published on: November 7, 2020
Social Determinants of Health and Liver Transplant Outcomes in U.S. Indigenous Populations
Bima J Hasjim1,2, Meera Patel2, Shiyi Chen2,3,4
1Department of Surgery, Division of Transplantation, University of California, Irvine, Orange, California, USA.
Introduction:
Indigenous populations in the United States (IPUS) have disproportionately high burden of end-stage liver disease but are relatively understudied.
Methods:
This retrospective study merged the Scientific Registry of Transplant Recipients Data set (2004-2024) with U.S. census data to estimate the exposure to social determinants of health (SDOH).
Results:
Of 164,294 patients, 0.9% identified as IPUS and resided in areas with more vulnerable SDOH ( P < 0.001). They were less likely to receive liver transplantation (LT) compared with non-IPUS patients (subdistribution hazard ratio 0.92; 95% confidence interval 0.85-0.99), but had similar risks of waitlist mortality, post-LT mortality, and graft failure.
Discussion:
IPUS face SDOH challenges and lower rates of LT after waitlisting but can still achieve post-LT outcomes similar to non-IPUS patients.
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