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Related Experiment Video

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Using Eye-tracking to Assess the Relative Importance of Visual and Vestibular Input to Subcortical Motion Processing in the Roll Plane
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Structural Brain Abnormalities, Diagnostic Approaches, and Treatment Strategies in Vertigo: A Case-Control Study.

Klaudia Széphelyi1, Szilvia Kóra1,2, Gergely Orsi3,4

  • 1Doctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, 7622 Pécs, Hungary.

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|September 26, 2025
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Summary

Magnetic Resonance Imaging (MRI) reveals structural brain changes in vertigo patients, including white matter lesions and infarcts. Pre-MRI diagnostics and multidisciplinary treatments are vital for managing dizziness and related conditions.

Keywords:
BPPVMRIbetahistinecircle of Willislifestyle modificationssinusitisvertigowhite matter lesions

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Area of Science:

  • Neurology
  • Radiology
  • Otolaryngology

Background:

  • Dizziness is a common symptom with diverse origins, including neurological, otolaryngological, and psychological factors.
  • Diagnostic imaging like CT, X-rays, and ultrasound are used, with MRI being essential for detecting brain abnormalities.

Purpose of the Study:

  • Identify structural brain changes associated with vertigo using MRI.
  • Assess the effectiveness of pre-MRI diagnostic approaches.
  • Evaluate current treatment strategies for vertigo.

Main Methods:

  • A case-control study involving 232 vertigo patients and 232 controls.
  • Analysis of MRI findings, pre-MRI examinations, patient symptoms, and treatment outcomes.
  • Statistical analysis using chi-square and t-tests to compare groups (p < 0.05).

Main Results:

  • Vertigo patients showed significantly higher frequencies of white matter lesions, lacunar infarcts, Circle of Willis variations, and sinusitis (p < 0.05).
  • Pre-MRI diagnostics identified atherosclerosis and spondylosis.
  • Benign Paroxysmal Positional Vertigo (BPPV) was the most common post-MRI diagnosis.

Conclusions:

  • MRI is effective in identifying structural brain changes linked to vertigo.
  • Pre-MRI assessments are crucial for excluding vascular and musculoskeletal etiologies.
  • A multidisciplinary approach combining lifestyle changes, physical therapy, and medication is recommended for vertigo management.