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Related Experiment Video

Updated: Jan 16, 2026

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Efficient Retinal Vessel Segmentation with 78K Parameters.

Zhigao Zeng1, Jiakai Liu1, Xianming Huang1

  • 1School of Computer Science, Hunan University of Technology, Zhuzhou 412007, China.

Journal of Imaging
|September 26, 2025
PubMed
Summary
This summary is machine-generated.

DSAE-Net offers accurate retinal vessel segmentation for diabetic retinopathy diagnosis using a lightweight dual-stage network. This efficient model reduces complexity while improving performance, aiding real-time clinical applications.

Keywords:
deep learningimage segmentationlightweight networksretinal vessel segmentationsegmentationself-attention

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Area of Science:

  • Medical Imaging
  • Deep Learning
  • Ophthalmology

Background:

  • Diabetic retinopathy diagnosis relies on retinal vessel segmentation.
  • Current deep learning models often face accuracy-complexity trade-offs.
  • Efficient segmentation is crucial for clinical settings.

Purpose of the Study:

  • To develop a lightweight yet accurate deep learning model for retinal vessel segmentation.
  • To address the limitations of existing models in terms of computational complexity and accuracy.
  • To facilitate early diagnosis of diabetic retinopathy.

Main Methods:

  • Proposed DSAE-Net, a dual-stage network featuring a Parameterized Cascaded W-shaped Architecture.
  • Introduced Skeleton Distance Loss (SDL) to manage class imbalance and boundary issues.
  • Developed Cross-modal Fusion Attention (CMFA) and Coordinate Attention Gates (CAGs) for enhanced feature refinement.
  • Utilized DRIVE, CHASE_DB1, HRF, and STARE datasets for evaluation.

Main Results:

  • DSAE-Net achieved superior segmentation accuracy compared to state-of-the-art lightweight models.
  • The proposed architecture significantly reduced computational complexity (using only 1% of U-Net parameters).
  • The model demonstrated robustness across multiple benchmark datasets.
  • SDL effectively handled severe class imbalance inherent in retinal images.

Conclusions:

  • DSAE-Net provides an efficient and accurate solution for retinal vessel segmentation.
  • The model's low complexity and high performance are suitable for real-time diagnostics.
  • This approach supports early detection of diabetic retinopathy in resource-limited environments.