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Intraoral vs. extraoral bitewing radiography for approximal caries detection: A multi-observer ex vivo ROC study
Julia Caroline Quintus1, Ralf Kurt Willy Schulze2
1Department of Orthodontics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Clinical Oral Investigations
|September 26, 2025
Summary
Intraoral bitewing radiography (iBWR) showed higher accuracy than extraoral bitewing radiography (eBWR) for detecting interproximal caries. Both methods had low reliability, and accuracy for early enamel lesions was minimal for both iBWR and eBWR.
Area of Science:
- Dental radiology
- Diagnostic imaging
- Caries detection
Background:
- Accurate detection of interproximal caries is crucial for timely dental treatment.
- Comparing intraoral bitewing radiography (iBWR) and extraoral bitewing radiography (eBWR) for caries detection is important for clinical practice.
Purpose of the Study:
- To compare the diagnostic accuracy of iBWR and eBWR in detecting natural interproximal carious lesions.
- To evaluate the performance of both radiographic techniques using a multi-observer design and a histological gold standard.
Main Methods:
- Eighty extracted teeth were mounted in a simulated jaw, with approximately 50% having caries.
- Images were acquired using iBWR with a CMOS sensor and eBWR with a digital panoramic device.
- Twenty-seven dentists assessed caries presence and depth, with results compared to histological analysis.
Main Results:
- Overall diagnostic accuracy was higher for iBWR (Az=0.58) than for eBWR (Az=0.54).
- Both intra-rater and inter-rater reliability were low for both methods.
- iBWR demonstrated higher specificity and positive predictive values for enamel caries, while eBWR showed higher initial sensitivity.
Conclusions:
- Intraoral bitewing radiography (iBWR) demonstrated superior diagnostic accuracy compared to extraoral bitewing radiography (eBWR) for interproximal caries detection.
- Despite higher accuracy, both methods showed limited diagnostic capability for early enamel lesions, performing just above random guessing.

