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Updated: Jul 17, 2026

Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
Novel flap designs for reconstructing the exenterated orbital cavity - A systematic review
Raffaele Aguglia1, Lucas Ungerer2, Nadia Benmoussa1
1Gustave Roussy, Paris-Saclay University, Department of Head and Neck Surgery, Villejuif, F-94805, France.
Orbital exenteration reconstruction presents challenges due to the orbit's shape. This review synthesizes flap techniques to improve outcomes and patient reintegration after this extensive surgery.
Area of Science:
- Reconstructive surgery
- Anaplastology
- Ophthalmology
Background:
- Orbital exenteration is a disfiguring surgery requiring mandatory reconstruction.
- The unique inverted cone shape of the exenterated orbit complicates surgical repair.
- Close collaboration between surgeons and anaplastologists is crucial for successful patient reintegration.
Purpose of the Study:
- To systematically review innovative flap design strategies for orbital exenteration reconstruction.
- To provide an updated framework for reconstructive surgeons.
- To improve functional and aesthetic outcomes, enhancing patient quality of life.
Main Methods:
- Systematic review following 2020 PRISMA guidelines.
- Protocol pre-registered in PROSPERO (ID: CRD420251149891).
- Selection of 11 studies from PubMed and Google Scholar databases.
Main Results:
- Evaluation of pedicled and free flap techniques including temporalis muscle, galeal, forehead, radial forearm, and lateral circumflex femoral artery flaps.
- Inclusion of 64 patients across selected studies.
- A combined prosthetic rehabilitation rate of 50% was observed.
Conclusions:
- Contemporary flap designs offer promising solutions for orbital exenteration reconstruction.
- Synthesizing novel approaches aids surgeons in planning reconstructions.
- Restoring form and function significantly improves patients' quality of life.
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