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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
Published on: July 11, 2025
807
The Rise of AI-Assisted Diagnosis: Will Pathologists Be Partners or Bystanders?
Riyad El-Khoury1, Ghazi Zaatari1
1Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut 1107 2020, Lebanon.
Diagnostics (Basel, Switzerland)
|September 27, 2025
Summary
Pathology has evolved from microscopy to digital pathology and artificial intelligence (AI). This review assesses if AI can achieve diagnostic autonomy, questioning the future role of pathologists in automated diagnostics.
Area of Science:
- Pathology
- Medical Technology
- Artificial Intelligence
Background:
- Pathology has evolved over 150 years from microscopic tissue examination to digital pathology and AI.
- Digital pathology overcame limitations of conventional microscopy, enabling AI integration.
- AI offers automated diagnostics, enhanced precision, accelerated research, and improved medical education.
Purpose of the Study:
- To review the evolution of pathology and digital pathology.
- To critically evaluate the feasibility, limitations, and implications of a pathologist-independent AI diagnostic model.
- To explore the future role of pathologists in an increasingly automated field.
Main Methods:
- Historical review of microscopy and pathology advancements.
- Analysis of digital pathology's impact on diagnostic workflows.
- Critical assessment of AI's potential for autonomous diagnostic capabilities.
Main Results:
- AI integration is revolutionizing pathology workflows with significant opportunities.
- Few studies critically examine the feasibility of fully autonomous AI diagnostics.
- The review uniquely addresses the potential for a pathologist-free diagnostic model.
Conclusions:
- AI's rapid advancement necessitates an examination of its potential for diagnostic autonomy.
- The evolving role of pathologists in the face of automation requires careful consideration.
- Assessing AI's ability to sustain diagnostic accuracy without pathologist oversight is crucial.

