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Related Concept Videos

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

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Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
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Immune Surveillance by NK Cells and Phagocytes01:25

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Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
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Antigens Involved in Adaptive Immunity01:26

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An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
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Subsequent T...
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Immunological Memory01:23

Immunological Memory

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Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
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Immune Response Against Viral Pathogens01:29

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The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
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Breast Cancer and Metabolic Dysfunction-Associated Steatotic Liver Disease.

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Updated: Jan 16, 2026

Immunometabolic Circuits in Infection for Advancing Host Directed Therapies
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Immunonutrition: Another Player on the MASLD Field.

Iván López-Méndez1, Misael Uribe2, Eva Juárez-Hernández3

  • 1Hepatology and Transplants Unit, Medica Sur Clinic & Foundation, Mexico City 14050, Mexico.

International Journal of Molecular Sciences
|September 27, 2025
PubMed
Summary
This summary is machine-generated.

Immunonutrition, using diet to modulate inflammation, is key for metabolic dysfunction-associated steatotic liver disease (MASLD). Personalized, locally adapted diets rich in immunonutrients are essential for MASLD management.

Keywords:
inflammationliver steatosisnutritionoxidative stress

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Area of Science:

  • Nutrition Science
  • Hepatology
  • Immunology

Background:

  • Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing chronic liver condition.
  • Inflammation and oxidative stress are central to MASLD progression.
  • Immunonutrition offers a strategy to modulate these pathways via dietary nutrients.

Purpose of the Study:

  • To highlight the importance of immunonutrition in MASLD management.
  • To discuss the limitations of current dietary guidelines (e.g., Mediterranean Diet) for MASLD.
  • To advocate for individualized and locally adapted dietary strategies.

Main Methods:

  • Review of immunonutrition principles and their application to MASLD.
  • Analysis of dietary patterns and their impact on liver health.
  • Consideration of factors influencing dietary adherence and accessibility.

Main Results:

  • The Mediterranean Diet, while rich in immunonutrients, faces accessibility challenges.
  • Immunonutrition strategies can complement pharmacological treatments and physical activity.
  • Dietary interventions must be tailored to individual patient characteristics and local food environments.

Conclusions:

  • Individualized dietary recommendations incorporating immunonutrients are crucial for effective MASLD treatment.
  • Adapting diets to local food availability enhances patient adherence and outcomes.
  • Immunonutrition represents a vital component of a comprehensive MASLD management plan.