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Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

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Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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Cardiac Catheterization I: Pre-Procedure Overview01:28

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Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Aortic Regurgitation I: Introduction01:15

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IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
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Related Experiment Video

Updated: Jan 16, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Redo-Transcatheter Aortic Valve Replacement: Current Evidence and Procedural Considerations.

Raviteja R Guddeti1, Hanad Bashir1, Puvi Seshiah1

  • 1Interventional and Structural Cardiology, The Carl and Edyth Lindner Research Center, The Christ Hospital, Cincinnati, OH 45219, USA.

Journal of Clinical Medicine
|September 27, 2025
PubMed
Summary
This summary is machine-generated.

Transcatheter aortic valve replacement (TAVR) is expanding to low-risk patients, but valve durability is a concern. Redo-TAVR procedures show promise for favorable short-term outcomes, with cardiac CT aiding planning.

Keywords:
aortic regurgitationaortic stenosisbioprosthetic valve dysfunctioncardiac computed tomography angiographyredo-transcatheter aortic valve replacement

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Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Medical Imaging

Background:

  • Severe aortic stenosis (AS) management has been transformed by transcatheter aortic valve replacement (TAVR).
  • Expanding TAVR indications to low-surgical-risk patients raises concerns about long-term transcatheter heart valve (THV) durability.
  • Redo-TAVR (TAVR-in-TAVR) is emerging as a feasible option for valve failure.

Purpose of the Study:

  • To review the feasibility and outcomes of redo-TAVR procedures.
  • To highlight the critical role of pre-procedure planning in redo-TAVR.
  • To emphasize the importance of understanding native aortic valve anatomy and index THV characteristics.

Main Methods:

  • Review of observational studies and registries on redo-TAVR.
  • Emphasis on the utilization of cardiac computed tomography angiography (CTA) for procedural planning.
  • Assessment of factors influencing technical and procedural success in redo-TAVR.

Main Results:

  • Redo-TAVR is technically feasible with favorable short-term outcomes reported in current literature.
  • Cardiac CTA is crucial for selecting appropriate valves and planning procedures, including risk assessment for coronary occlusion.
  • Understanding patient-specific anatomy and prior valve characteristics is key for successful redo-TAVR.

Conclusions:

  • Redo-TAVR is a viable option for managing failing THVs, particularly in the context of expanding TAVR use.
  • Accurate pre-procedural assessment using CTA is essential for optimizing outcomes and mitigating risks.
  • Further evidence from prospective registries is needed to fully elucidate long-term clinical and hemodynamic results of redo-TAVR.