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Updated: Jan 16, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
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Gut microbiota-derived histamine exacerbates psoriasis by promoting γδT17 cell differentiation via the Hrh1/Wnt Axis

Waiming Cheng1, Meihong He1, Elfira Jurat1

  • 1The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, Guangdong 510317, China; State Key Laboratory of Bioactive Molecules and Druggability Assessment, The Biomedical Translational Research Institute, Health Science Center (School of Medicine), Jinan University, Guangzhou 510632, China.

International Immunopharmacology
|September 27, 2025
PubMed
Abstract

Keywords:
Gut microbiotaHistamineHrh1 receptorPsoriasisWnt signaling pathwayγδT17 cells

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