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Updated: Jan 16, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Effects of three peripherally inserted central catheters insertion techniques on catheterization outcomes: A
Lan Li1, Xinlei Wu2, Lihui Lin3
1Department of Pediatrics, Intravenous Therapy Specialty Clinic, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
One-needle subcutaneous tunnel catheterization offers superior outcomes compared to traditional methods for peripherally inserted central catheters (PICC). This technique improves puncture success rates and reduces bleeding and pain, making it ideal for clinical practice.
Area of Science:
- Medical Procedures
- Vascular Access Devices
- Clinical Trials
Background:
- Current peripherally inserted central catheters (PICC) methods include traditional, one-needle, and two-needle subcutaneous tunnel techniques.
- Research often overlooks the procedural aspects of PICC insertion, focusing instead on post-catheterization complications.
- Key procedural factors like first-attempt success, patient experience, and bleeding are critical for evaluating PICC methods.
Purpose of the Study:
- To compare the procedural outcomes of traditional non-tunnel catheterization with one-needle and two-needle subcutaneous tunnel catheterization for PICC insertion.
- To evaluate the impact of different PICC insertion techniques on first-time puncture success, patient pain, and bleeding.
Main Methods:
- A three-arm, parallel, randomized controlled trial was conducted with 681 patients.
- Patients were randomized into traditional non-tunnel, one-needle subcutaneous tunnel, or two-needle subcutaneous tunnel catheterization groups.
- Primary outcomes included one-time puncture success rate, pain intensity, and total bleeding volume.
Main Results:
- One-needle and two-needle subcutaneous tunnel methods showed significantly higher one-time puncture success rates than the traditional method.
- Both tunnel methods resulted in a lower blood oozing rate within 24 hours post-catheterization compared to the traditional method.
- The traditional and one-needle methods had significantly lower total bleeding volume, pain intensity, and catheterization operating time compared to the two-needle method.
Conclusions:
- One-needle subcutaneous tunnel catheterization demonstrated superior performance over traditional and two-needle methods.
- This technique is associated with improved procedural success and patient comfort, with no reported nerve or blood vessel damage.
- One-needle subcutaneous tunnel catheterization is recommended for clinical application.
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