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Updated: Jan 16, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Stereoselective Synthesis of π-Enriched Conjugated Dienynals via Photochemical Alkynyl Carbene Insertion into Furans
Paru Jamwal1, Ritik Shukla1, Ramani Gurubrahamam1
1Department of Chemistry, Indian Institute of Technology Jammu, NH-44, PO Nagrota, Jagti, Jammu and Kashmir, 181221, India.
Abstract:
The first photochemical carbene insertion reaction into furans is developed for the stereoselective synthesis of π-extended conjugated dienynal and dienynone scaffolds. The protocol harnesses sustainable visible light and does not demand any additives or photocatalysts. It provides a wide variety of densely functionalized dienynal/dienynone carboxylates in good yields with excellent selectivity (40 examples, up to 83% yield and (2E, 4E)-isomer). Furthermore, the developed strategy is scalable, and the downstream transformations are demonstrated toward obtaining valuable products.
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