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Pet-human transmission of CTX-M-8 extended-spectrum β-lactamase-producing Escherichia coli ST961 and phylogenetic
Luciana Sartori1, Fábio P Sellera2, João Pedro Rueda Furlan3
1Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.
Diagnostic Microbiology and Infectious Disease
|September 28, 2025
Abstract:
Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli pose a One Health concern. We report potential transmission of a CTX-M-8-producing E. coli ST961 strain between a French Bulldog and its owner. Both isolates showed similar antimicrobial resistance and virulence profiles, with only 30 SNP differences, highlighting zoonotic transmission risk and integrated health strategies.

