Case Report: Relapsing pleural effusions and coated aorta revealing Erdheim-Chester disease

Tiépé Rokia Ouattara1, Théo Pezel2, Gwenael Lorillon3

  • 1Department of Internal Medicine, Lariboisière Hospital, Assistance Publique des hôpitaux de Paris (APHP), Université Paris Cité, Paris, France.

Frontiers in Immunology
|September 29, 2025
PubMed
Summary

Erdheim-Chester disease (ECD) diagnosis can be challenging due to its rarity and varied symptoms. This case highlights recurrent pleural effusions as an unusual initial sign, with genetic testing confirming a MAP2K1 mutation.

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