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Published on: February 1, 2018
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Home-Based Noninvasive Spinal Cord Stimulation Safely Enhances Hand and Arm Function in People With Spinal Cord
Candace Tefertiller1, Randy D Trumbower2, Leslie Morse3
1Research Department, Craig Hospital, Denver, CO.
Neurology. Clinical Practice
|September 29, 2025
Summary
Home-based noninvasive spinal cord stimulation (ARCEX Therapy) safely improved upper extremity function in chronic incomplete cervical spinal cord injury (SCI) patients. This therapy is crucial for maintaining in-clinic gains and enhancing functional recovery.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Biomedical Engineering
Background:
- Chronic incomplete cervical spinal cord injury (SCI) significantly impairs upper extremity function.
- In-clinic rehabilitation with noninvasive spinal cord stimulation (ARCEX Therapy) has shown efficacy in improving strength and function.
- The LIFT Home trial investigated the transition of ARCEX Therapy to a home-based setting.
Purpose of the Study:
- To evaluate the safety and usability of at-home ARCEX Therapy for individuals with chronic incomplete cervical SCI.
- To assess the benefits of continued home-based therapy on upper extremity strength, function, and quality of life.
- To determine if home-based therapy can maintain or extend improvements achieved during in-clinic treatment.
Main Methods:
- A single-arm interventional trial involving 17 participants who previously underwent in-clinic ARCEX Therapy.
- Participants used ARCEX Therapy at home for one month, with primary endpoints focusing on safety and feasibility.
- Secondary outcomes included standardized tests for upper extremity function (CUE-T), strength, pain, psychological health, and independence.
Main Results:
- No serious adverse events or major usability issues were reported, indicating safe and feasible home use.
- High compliance with prescribed therapy was observed, mirroring in-clinic dosages.
- Significant improvements were noted in upper extremity function (CUE-T scores), pinch force, pain interference, psychological health, and self-care ability.
Conclusions:
- At-home ARCEX Therapy is a safe and effective method for continuing to improve strength and function in individuals with chronic incomplete cervical SCI.
- Home-based therapy plays a vital role in maintaining treatment gains achieved in clinical settings and potentially enhancing further recovery.
- The findings support the integration of home-based noninvasive spinal cord stimulation as a key component of long-term SCI rehabilitation.
