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Updated: Jan 6, 2026

Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
Published on: January 7, 2016
History and Current Status of Growth Hormone Treatment in Children
Camila C Luz1, Paulo F Collett-Solberg2
1Laboratório de Pesquisas Clínicas e Experimentais em Biologia Vascular (BioVasc) and Discipline of Endocrinology, Department of Internal Medicine of Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rua São Francisco Xavier, 524, Pav. Haroldo Lisboa da Cunha sala 104, Maracanã, Rio de Janeiro, RJ, 20550-170, Brazil.
Abstract:
Growth hormone (GH) has been used to treat severe GH deficiency for more than 60 years, with other indications dependent upon approval from national medical societies and governmental agencies. Many changes in GH preparations have been made to improve safety, compliance, and efficacy, from the extraction of GH from human pituitary glands to recombinant hormone technology and from the use of vials and syringes to the use of more advanced devices. Adherence to treatment has always been highlighted as a key point in the success of treatment; new depot preparations permitting weekly administration have advantages in this regard. This review summarizes the history of GH use and provides an analysis of the new weekly administration products.
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