Top 10 priorities for future ectopic pregnancy research: an international consensus development study

Area of Science:

• Reproductive Health
• Medical Research Prioritization

Background:

• Ectopic pregnancy poses significant health risks, necessitating focused research to improve outcomes.
• Current research gaps hinder effective prevention and treatment strategies for ectopic pregnancy.

Purpose of the Study:

• To determine and prioritize future research directions for ectopic pregnancy.
• To establish a consensus-driven agenda for ectopic pregnancy research.

Main Methods:

• A multi-stage international process involving surveys, systematic reviews, and a consensus development meeting.
• Utilized the modified nominal group technique with diverse stakeholders, including healthcare professionals and patients.
• Collated research questions from 855 initial survey participants, clinical guidelines, and Cochrane reviews.

Main Results:

• Identified 10 key research priorities for ectopic pregnancy from 49 confirmed uncertainties.
• The consensus involved 37 participants from 10 countries, reflecting global perspectives.
• Priorities encompass prevention, treatment modalities, and understanding the longer-term consequences of ectopic pregnancy.

Conclusions:

• The identified priorities address critical clinical needs in ectopic pregnancy care.
• This research agenda aims to guide funding organizations and researchers toward impactful future studies.
• The findings will help shape the future research landscape for ectopic pregnancy.