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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Lipid Profile of Patients with Ischemic Stroke Involving Anterior Circulation Admitted in a Tertiary Care Hospital
M Fakruzzaman1, S M J Bhuya, M K Podder
1Dr Md Fakruzzaman, Junior Consultant (Medicine), Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh;
Insights
This study found that nearly half of ischemic stroke patients had abnormal lipid profiles, with hypertension being a major risk factor. Managing lifestyle and risk factors is crucial for stroke prevention.
Area of Science:
- Neurology
- Cardiology
- Public Health
Background:
- Stroke is a leading global cause of disability and mortality.
- Ischemic stroke, particularly involving anterior circulation, presents a significant health challenge.
Purpose of the Study:
- To investigate lipid profile abnormalities in patients with ischemic stroke in Bangladesh.
- To identify common risk factors associated with ischemic stroke in the studied population.
Main Methods:
- An observational study conducted at a tertiary-level hospital in Bangladesh.
- Inclusion of 100 hospitalized adult patients diagnosed with stroke.
- Data collection on patient demographics, lifestyle, and lipid profiles.
Main Results:
- Hypertension was a prevalent risk factor (72.0%), followed by smoking (40.0%) and diabetes mellitus (15.0%).
- 48.0% of patients exhibited elevated serum cholesterol levels (>200 mg/dl).
- Abnormalities in Low Density Lipoprotein (LDL) Cholesterol (12.0%), High Density Lipoprotein (HDL) Cholesterol (6.0%), and triglycerides (20.0%) were observed.
Conclusions:
- Lipid profile abnormalities are common in patients with ischemic stroke.
- Hypertension, smoking, and diabetes are significant risk factors requiring management.
- Addressing dietary habits, lifestyle, and known risk factors is vital for the primary prevention of stroke.
Abstract:
Stroke is a global health problem. It is the leading cause of disability and the second leading cause of mortality worldwide. This observational study was carried out in the Department of Medicine and Department of Neurology, Mymensingh Medical College Hospital, Bangladesh a tertiary-level academic and treatment-based hospital in Bangladesh from 1st July 2013 to 31st December 2013, to find out the abnormalities of lipid profile of patients of ischemic stroke involving anterior circulation. Patients having a history of stroke were enrolled in the study after getting informed written consent from the patient or attendant. One hundred hospitalized adult patients with stroke were selected for the study based on inclusion and exclusion criteria. Fifty-one percent (51.0%) of patients were accustomed to leading a sedentary lifestyle. The majority of the patients hailed from urban areas of Bangladesh and seventy-eight percent had a habit of experiencing active lifestyle patterns. Among the risk factors, it was observed that hypertension was a major (72.0% cases) risk factor for stroke. Diabetes mellitus was detected in 15.0% of cases. The majority were Type-2 Diabetes mellitus. Forty percent (40.0%) of the patients were smokers in various forms. The majority of patients (52.0%) have normal serum cholesterol within normal limits (<200 mg/dl), but in more cases 48.0% above the normal limit (>200 mg/dl), 12.0% cases have raised Low Density Lipoprotein (LDL) Cholesterol (>190 mg/dl), only 6.0% cases have low (<100 mg/dl) High Density Lipoprotein (HDL) Cholesterol and 20.0% cases have raised serum triglyceride (TG) level (>200 mg/dl). So, we should think about known dietary habits, lifestyle and risk factors of stroke, proper control of which plays an important role in the primary prevention of the disease.
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