Effect on Serum Calcium in Patients with Type 2 Diabetes Mellitus

Diabetes mellitus is a syndrome of impaired carbohydrate, fat and protein metabolism caused by either lack of insulin secretion or decreased sensitivity of the tissues to insulin. The cross sectional study was performed in the department of Biochemistry, Mymensingh Medical College from July 2021 to June 2022 with the approval of the institutional review board (IRB) of Mymensingh Medical College. Total 100 subjects were included in this study. Out of them, 50 were selected as Group I and 50 as Group II. Group I noted as known case of Type 2 diabetes mellitus patients (diagnosed according to history and fasting serum glucose level ≥7.0 mmol/L and 2 hours after breakfast serum glucose level ≥11.1 mmol/L) age ranging from 35-65 years; where as Group II apparently healthy people of same age group. Serum Calcium was determined by colorimetric method with cresolphthalein. Pre assessed data were recorded in a collection sheet. Statistical analysis was done by using SPSS (Statistical Package for Social Science) version 26.0 windows package. Unpaired t' test was done between Group I and Group II. The difference in mean BMI was not significant (p>0.05). The mean ±SD values of serum calcium were 9.65±0.40 mg/dl and 11.02±0.70 mg/dl in Group I and Group II respectively. Serum calcium was decreased markedly in patients with Type 2 diabetes mellitus. So, early evaluation of Serum calcium (Ca) may reduce the complications of type 2 diabetes mellitus.