A step-by-step guide for cardiac computed tomography ventricular volumetry using three-dimensional threshold-based

Hyun Woo Goo1, Haifa Abdul Latiff2

  • 1Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. ghw68@hanmail.net.

Pediatric Radiology
|October 1, 2025
PubMed

Insights

Cardiac computed tomography (CT) can assess ventricular function in pediatric congenital heart disease. A 3D segmentation method improves accuracy for CT-based ventricular volumetry, offering a valuable alternative when MRI is not feasible.

Area of Science:

  • Cardiovascular Imaging
  • Pediatric Cardiology
  • Medical Physics

Background:

  • Cardiac computed tomography (CT) offers high spatial resolution and short scan times for evaluating ventricular function in children with congenital heart disease (CHD).
  • Cardiac magnetic resonance imaging (MRI) is often the preferred modality, but CT serves as a crucial alternative when MRI is unavailable, inadequate, or contraindicated.
  • Assessing ventricular function with CT requires higher radiation doses than morphological evaluation, necessitating careful consideration of radiation exposure.

Purpose of the Study:

  • To present a step-by-step guide for cardiac CT ventricular volumetry using 3D threshold-based segmentation in pediatric CHD.
  • To highlight the advantages of 3D segmentation over conventional methods for accurate and reproducible ventricular volume assessment.
  • To provide a practical approach for clinicians utilizing CT for functional assessment in CHD.

Main Methods:

  • Detailed methodology for performing cardiac CT with a focus on achieving high spatial resolution and short scan times.
  • Explanation of the 3D threshold-based segmentation technique for ventricular volumetry.
  • Comparison of the 3D segmentation approach with conventional 2D disc summation and simplified contouring methods.

Main Results:

  • The 3D threshold-based segmentation approach demonstrates superior accuracy and reproducibility for ventricular volumetry compared to conventional methods.
  • This advanced segmentation technique overcomes limitations of simplified contouring and 2D summation in volumetric analysis.
  • Cardiac CT, particularly with 3D segmentation, provides a viable option for ventricular function assessment in CHD.

Conclusions:

  • Cardiac CT with 3D threshold-based segmentation is an accurate and reproducible method for ventricular volumetry in pediatric CHD.
  • This technique offers a valuable alternative to MRI, especially in cases where MRI is not feasible.
  • Guidelines for implementing this advanced CT analysis are essential for clinical practice in CHD management.